Friday, December 9, 2011

KIDNEY STRUCTURE NEPHRON!

The Kidney are highly vascular organ, they receive approximately 25% of the cardiac output. The kidney produce urine, initail a glomerular ultrafiltrate of the blood or primary urine, which is then modified by selective resorption and specific secretion by the cells of the kidney. The final urine is conveyed by the ureters to the urinaru bladder, it is stored until discharged via the urethra.
The Kidney are large, reddish, bean-shaped organ located on either side of the spinal column in the retroperitoneal spacxe of the posterior abdominal cavity. The picture will show the structure, flow of blood in the tubule and how the reasorption works:


Capsule: The Kidney surface is covered by a connective tissue capsule. The capsule consists of two distinct layers: an outer layer of fibroblasts and collagen fibers, and an inner layer with cellular component of myofibroblast.
Function:
-Synthesis and secretion of the glycoprotein hormone erythropoietin (EPO)
- Synthesis and secretion of the acid protease renin, an enzyme involve in control of blood pressure and blood volume.
-Hydroxylation of 25-OH vitamin D3, a steriod presursor produced in the liver.

Reference:
www.humanbodyreviews.com
Histology A Text and Atlas. Author: Michael H. Ross, Wojciech Pawlina. Sixth Edition.

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